Description

3-Fluoro-5-Iodo-Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, offers versatile reactivity for selective cross-coupling and functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that leverage the stability and bioactivity of fluorinated heterocycles.
• Material Science Research: Used in the creation of specialized ligands for catalysis and as a monomer or functionalizing agent for advanced polymers and electronic materials.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki-Miyaura, Stille, and other palladium-catalyzed coupling reactions due to the reactive iodine moiety.
• Chemical Biology & Diagnostics: Employed in the synthesis of molecular probes, tags, and imaging agents for biochemical research and diagnostic applications.

Basic Information

Product Name	3-Fluoro-5-Iodo-Pyridine
CAS No.	757950-13-3
Molecular Formula	C5H3FIN
Molecular Weight	222.99 g/mol
Synonyms	5-Iodo-3-fluoropyridine; 3-Fluoro-5-iodopyridine; 3-F-5-I-Pyridine; Pyridine, 3-fluoro-5-iodo-; 5-Iodo-3-fluoro-pyridine; 3-Fluoropyridin-5-yl iodide; 3-Fluoro-5-iodo-pyridin
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Iodo-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.