Description

Ethyl 1-Thio-D-Glucuronide is a specialized thioglycoside derivative of D-glucuronic acid, serving as a crucial biochemical tool and synthetic intermediate. This compound is valued for its role in metabolic pathway studies and as a precursor for synthesizing more complex glycoconjugates and enzyme substrates. It is primarily utilized by research institutions and pharmaceutical companies engaged in glycobiology research, drug metabolism investigations, and the development of diagnostic agents.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to glucuronidation and glycosidase activity.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of prodrugs or targeted therapeutic agents that utilize glucuronide pathways for activation or detoxification.
• Metabolite Synthesis: Employed in the preparation of stable isotope-labeled or fluorescent-tagged glucuronide metabolites for analytical standards and assay development.
• Glycoconjugate Chemistry: Acts as a building block for the chemical synthesis of complex oligosaccharides, glycopeptides, and other neoglycoconjugates.
• Diagnostic Reagents: Potential use in formulating reagents for clinical diagnostics that detect or quantify specific enzymatic activities.

Basic Information

Product Name	Ethyl 1-Thio-D-Glucuronide
CAS No.	755710-39-5
Molecular Formula	C8H14O7S
Molecular Weight	254.26 g/mol
Synonyms	Ethyl 1-Thio-β-D-Glucopyranosiduronic Acid; Ethyl 1-Thio-β-D-Glucuronide; 1-S-Ethyl-1-thio-β-D-glucuronic acid; Ethyl β-D-Thioglucuronide; 1-Thioethyl D-Glucuronate; ETG (context-specific); β-D-Glucopyranosiduronic acid, 1-thioethyl-
EINECS	Contact for details

Quality Control

Our Ethyl 1-Thio-D-Glucuronide is produced under a quality-managed system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), optical rotation, and impurity profiles are available upon request to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.