Description

Benzene, 1-Ethyl-3,5-Bis(Trifluoromethyl)- CAS NO 752244-58-9 is a specialized fluorinated aromatic compound characterized by its unique trifluoromethyl substituents. This structure is engineered to impart exceptional chemical stability and specific electronic properties, making it a valuable intermediate for advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl groups enhance lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for advanced polymers and liquid crystals, leveraging its fluorine content to alter surface energy and optical properties.
• Organic Electronics: Investigated as a component or intermediate in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Catalyst Ligand Development: The electron-withdrawing trifluoromethyl groups make it a candidate for designing novel ligands in transition metal catalysis.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research focused on introducing fluorinated motifs into organic frameworks.

Basic Information

Product Name	Benzene, 1-Ethyl-3,5-Bis(Trifluoromethyl)-
CAS No.	752244-58-9
Molecular Formula	C10H7F6
Molecular Weight	244.15 g/mol
Synonyms	1-Ethyl-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)ethylbenzene; Ethyl-3,5-bis(trifluoromethyl)benzene; 1-Ethyl-3,5-di(trifluoromethyl)benzene; 3,5-Di(trifluoromethyl)ethylbenzene; (3,5-Bis(trifluoromethyl)phenyl)ethane; m,m-Bis(trifluoromethyl)ethylbenzene
EINECS	Contact for details

Quality Control

Our production of 1-Ethyl-3,5-Bis(Trifluoromethyl)benzene adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques including GC, HPLC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.35 g/mL
Refractive Index (n20D)	~1.38

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.