Description

6-Chloropyrazine-2-Sulfonyl Chloride is a versatile and highly reactive bifunctional intermediate, serving as a critical building block in advanced organic synthesis. Its dual functionality as both a sulfonyl chloride and a chlorinated heterocycle makes it indispensable for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the pyrazine scaffold for bioactivity.
• Material Science Research: Acts as a monomer or cross-linking agent in the creation of specialized polymers and functional materials.
• Chemical Biology Probes: Employed in the design of activity-based probes and covalent inhibitors for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	6-Chloropyrazine-2-Sulfonyl Chloride
CAS No.	750584-04-4
Molecular Formula	C4H2Cl2N2O2S
Molecular Weight	228.04 g/mol
Synonyms	2-Chloro-6-sulfonylchloride pyrazine; 2,6-Dichloropyrazine-1-sulfonyl chloride; 6-Chloro-2-pyrazinesulfonyl chloride; 6-Chloropyrazine-2-sulfonylchloride; 2-Pyrazinesulfonyl chloride, 6-chloro-; 750584-04-4; 6-Chloro-2-sulfonylchloridopyrazin
EINECS	Contact for details

Quality Control

Every batch of 6-Chloropyrazine-2-Sulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.