Description

(1S)-2,2,2-Trifluoro-1-(3-Pyridyl)-Ethylamine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its core value lies in the trifluoromethyl group and pyridine moiety, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty chemicals and functional materials, such as liquid crystals or organic semiconductors.
• Chemical Biology Probes: Utilized as a building block for fluorinated probes and tags in medicinal chemistry and biochemical research.

Basic Information

Product Name	(1S)-2,2,2-Trifluoro-1-(3-Pyridyl)-Ethylamine
CAS No.	749839-26-7
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	(S)-1-(3-Pyridyl)-2,2,2-trifluoroethylamine; (1S)-1-(Pyridin-3-yl)-2,2,2-trifluoroethanamine; (S)-α-(Trifluoromethyl)-3-pyridinemethanamine; (S)-3-(1-Amino-2,2,2-trifluoroethyl)pyridine; (S)-TFMPA; (S)-Trifluoromethylpyridylethylamine; (S)-TFE-3-Py
EINECS	Contact for details

Quality Control

Our (1S)-2,2,2-Trifluoro-1-(3-Pyridyl)-Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.