Description

2-Hydroxy-4-Methyl-6-(Trifluoromethyl)-Pyridine is a specialized heterocyclic compound featuring a pyridine core substituted with hydroxyl, methyl, and trifluoromethyl groups. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel active ingredients. It is primarily utilized by pharmaceutical and agrochemical R&D teams seeking to incorporate fluorine-containing motifs to enhance the biological activity and metabolic stability of their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system, oncology, and anti-infectives.
• Agrochemical Synthesis: Serves as a crucial precursor for creating novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and biological efficacy.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to develop new ligands for transition metal complexes.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers and advanced organic electronic materials.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the synthesis and reactivity of fluorinated heterocycles.

Basic Information

Item	Detail
Product Name	2-Hydroxy-4-Methyl-6-(Trifluoromethyl)-Pyridine
CAS No.	749256-84-6
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	6-(Trifluoromethyl)-4-methylpyridin-2-ol; 4-Methyl-6-(trifluoromethyl)pyridin-2-ol; 2-Hydroxy-4-methyl-6-trifluoromethylpyridine; 2-Pyridinol, 4-methyl-6-(trifluoromethyl)-; 4-Methyl-6-(trifluoromethyl)-2-pyridone; 2-Hydroxy-4-methyl-6-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-Methyl-6-(Trifluoromethyl)-Pyridine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.