Description

1-Phenyl-5-Trifluoromethyl-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester is a high-value pyrazole derivative, a crucial synthetic intermediate prized for its trifluoromethyl group and aromatic functionality. This compound matters for its role in constructing complex molecules, particularly in the development of advanced agrochemicals and pharmaceuticals where the CF3 moiety enhances biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in areas targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Serves as a critical precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole and trifluoromethyl groups.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials requiring specific fluorinated aromatic structures.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging reagent in the design of chemical probes for studying enzyme function and protein interactions.
• Academic & Industrial R&D: A versatile starting material for methodological chemistry research, including cross-coupling reactions and heterocycle functionalization studies.

Basic Information

Product Name	1-Phenyl-5-Trifluoromethyl-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester
CAS No.	741717-63-5
Molecular Formula	C13H11F3N2O2
Molecular Weight	284.24 g/mol
Synonyms	Ethyl 1-Phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate; 1H-Pyrazole-4-carboxylic acid, 1-phenyl-5-(trifluoromethyl)-, ethyl ester; Ethyl 1-phenyl-5-trifluoromethylpyrazole-4-carboxylate; 5-Trifluoromethyl-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester; 741717-63-5; 1-Phenyl-5-trifluoromethylpyrazole-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1-Phenyl-5-Trifluoromethyl-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.