Description

(3-[4-(Trifluoromethyl)Phenyl]Phenyl)Sulfonylchloride is a high-purity, specialized organosulfur compound primarily used as a key synthetic intermediate in advanced chemical synthesis. Its value lies in the reactive sulfonyl chloride group and the stable, lipophilic trifluoromethylphenyl moiety, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for creating sulfonamide derivatives and other functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those containing sulfonamide pharmacophores with enhanced metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and advanced organic materials with specific surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and labeling reagents for studying enzyme function and protein interactions.
• Liquid Crystal & OLED Materials: A potential precursor for creating charge-transport or emissive layers in electronic displays and devices due to its aromatic and electron-withdrawing characteristics.

Basic Information

Product Name	(3-[4-(Trifluoromethyl)Phenyl]Phenyl)Sulfonylchloride
CAS No.	731779-91-2
Molecular Formula	C13H8ClF3O2S
Molecular Weight	320.71 g/mol
Synonyms	3'-(Trifluoromethyl)biphenyl-3-sulfonyl chloride; [1,1'-Biphenyl]-3-sulfonyl chloride, 3'-(trifluoromethyl)-; 3-(4-Trifluoromethylphenyl)benzenesulfonyl chloride; 3'-(Trifluoromethyl)-[1,1'-biphenyl]-3-sulfonyl chloride; (3'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our (3-[4-(Trifluoromethyl)Phenyl]Phenyl)Sulfonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0 - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.