Description

2-Chloro-3-Hydroxy-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and halogenated pyridine core, makes it a critical intermediate for developing novel active compounds. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, catalysts, and functional polymers.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and tool compounds for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring this specific halogenated pyridine derivative.

Basic Information

Product Name	2-Chloro-3-Hydroxy-4-(Trifluoromethyl)Pyridine
CAS No.	731002-59-8
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	4-(Trifluoromethyl)-2-chloro-3-hydroxypyridine; 2-Chloro-3-hydroxy-4-(trifluoromethyl)pyridine; 3-Hydroxy-2-chloro-4-trifluoromethylpyridine; 2-Chloro-4-(trifluoromethyl)pyridin-3-ol; 731002-59-8; 2-Chloro-3-hydroxy-4-trifluoromethylpyridine; 3-Pyridinol, 2-chloro-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Hydroxy-4-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.