Description

Abamine CAS NO 729612-64-0 is a specialized chemical compound belonging to the class of enzyme inhibitors, specifically targeting S-adenosylmethionine decarboxylase (AdoMetDC). This compound is valued for its role as a research tool in biochemical and pharmacological studies, enabling the investigation of polyamine biosynthesis pathways. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical R&D, and academic sectors for studying cell proliferation, apoptosis, and as a potential lead in therapeutic development.

Application

• Biochemical Research: Used as a potent and selective inhibitor of S-adenosylmethionine decarboxylase (AdoMetDC) in enzymatic assays and pathway studies.
• Pharmaceutical R&D: Serves as a key research compound for investigating the role of polyamine metabolism in diseases such as cancer, parasitic infections, and neurodegenerative disorders.
• Cell Biology Studies: Employed to modulate intracellular polyamine levels, facilitating research into cell growth, differentiation, and programmed cell death (apoptosis).
• Antiparasitic Agent Development: Investigated for its potential efficacy against trypanosomatid parasites, including those causing African sleeping sickness and leishmaniasis.
• Academic Research: A standard reagent in university and institutional labs for teaching and advanced research in metabolism and enzymology.
• Lead Compound Optimization: Acts as a structural scaffold for the design and synthesis of novel analogs with improved pharmacokinetic properties.

Basic Information

Product Name	Abamine
CAS No.	729612-64-0
Molecular Formula	C14H21N3O3S
Molecular Weight	311.40 g/mol
Synonyms	Abamine; 4-Amino-4-carboxybutyl methylsulfonium salt; AdoMetDC Inhibitor; S-Adenosylmethionine decarboxylase inhibitor; MDL 73811 analog; (4-Amino-4-carboxybutyl)(methyl)sulfanium
EINECS	Contact for details

Quality Control

Our Abamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.