Description

2-o-Tolyl-Ethanesulfonyl Chloride is a specialized organosulfur reagent primarily used as a key sulfonylation building block in advanced organic synthesis. Its value lies in its ability to introduce the o-tolyl-ethanesulfonyl moiety, a functional group of significant interest in medicinal chemistry and materials science. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of potential drug candidates, particularly in creating sulfonamide-based molecules with targeted biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that utilize sulfonyl groups for enhanced efficacy.
• Chemical Biology & Proteomics: Serves as a reagent for modifying proteins, peptides, or other biomolecules to study function or create bioconjugates.
• Material Science Research: Employed in the synthesis of novel polymers, ligands for catalysis, or organic electronic materials where the sulfonyl chloride group enables precise functionalization.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical producers offering bespoke synthesis services to clients in R&D.

Basic Information

Product Name	2-o-Tolyl-Ethanesulfonyl Chloride
CAS No.	728919-61-7
Molecular Formula	C9H11ClO2S
Molecular Weight	218.70 g/mol
Synonyms	2-(2-Methylphenyl)ethanesulfonyl chloride; o-Tolylethanesulfonyl chloride; 2-(o-Tolyl)ethanesulfonyl chloride; 1-Chlorosulfonyl-2-(2-methylphenyl)ethane; 2-Methylphenethylsulfonyl chloride; (2-Methylphenyl)ethanesulfonyl chloride; 2-(2-Methylphenyl)ethylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-o-Tolyl-Ethanesulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.