Description

2-(3-Chloro-Phenyl)-Ethanesulfonyl Chloride is a specialized organosulfur compound that serves as a critical building block in advanced organic synthesis. Its bifunctional reactive nature makes it an essential intermediate for constructing complex molecules with sulfonyl and aryl chloride functionalities. This high-purity intermediate is primarily sought by research and development teams and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonyl chloride group is incorporated for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Product Name	2-(3-Chloro-Phenyl)-Ethanesulfonyl Chloride
CAS No.	728919-59-3
Molecular Formula	C8H8Cl2O2S
Molecular Weight	239.12 g/mol
Synonyms	3-Chlorophenylethanesulfonyl Chloride; 1-(3-Chlorophenyl)ethanesulfonyl Chloride; 2-(3-Chlorophenyl)ethanesulfonyl Chloride; 3-Chloro-α-toluenesulfonyl Chloride; (3-Chlorophenyl)methanesulfonyl Chloride, Ethyl Homolog; m-Chlorophenylethanesulfonyl Chloride; 728919-59-3; 2-(3-Chlorophenyl)ethane-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chloro-Phenyl)-Ethanesulfonyl Chloride is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.