Description

5-[(Azepane-1-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride is a specialized organic intermediate featuring a reactive sulfonyl chloride group and a protected amine moiety. This compound is of significant value in pharmaceutical and advanced materials research for constructing complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and custom synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Research: Used in the creation of new active ingredients for crop protection agents, leveraging its structural complexity for targeted biological activity.
• Chemical Biology Probe Development: Serves as a precursor for labeling reagents and activity-based probes used to study enzyme function and protein interactions.
• Polymer & Material Science: Employed in the synthesis of functional monomers or cross-linking agents for advanced polymers with specific sulfonamide-based properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to client-specific molecular targets.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	5-[(Azepane-1-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-95-7
Molecular Formula	C₁₇H₁₉ClN₂O₃S
Molecular Weight	366.86 g/mol
Synonyms	5-[(azepane-1-carbonyl)amino]naphthalene-1-sulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-[(azepan-1-ylcarbonyl)amino]-; 5-(azepane-1-carboxamido)naphthalene-1-sulfonyl chloride; N-(1-sulfonylchloridonaphthalen-5-yl)azepane-1-carboxamide; Azepane-1-carboxylic acid [5-(chlorosulfonyl)-1-naphthyl]amide
EINECS	Contact for details

Quality Control

Every batch of 5-[(Azepane-1-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and reliability for research and development purposes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.