Description

5-(3,3-Dimethyl-Ureido)-Naphthalene-1-Sulfonyl Chloride is a specialized sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive sulfonyl chloride group, which enables efficient conjugation and derivatization reactions, making it essential for creating complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for creating sulfonamide-based molecules with targeted biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the sulfonyl urea moiety can impart specific modes of action.
• Fluorescent Probe & Dye Synthesis: The naphthalene core makes it suitable for constructing fluorescent tags and dyes for bio-imaging and diagnostic applications.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored properties.
• Chemical Biology Tool: Employed in activity-based protein profiling (ABPP) and other chemoproteomic studies to label and study enzyme active sites.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for client-specific projects requiring high-purity, complex organic intermediates.

Basic Information

Product Name	5-(3,3-Dimethyl-Ureido)-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-94-6
Molecular Formula	C₁₃H₁₃ClN₂O₃S
Molecular Weight	312.77 g/mol
Synonyms	1-Naphthalenesulfonyl chloride, 5-[(dimethylamino)carbonyl]amino]-; 5-[(Dimethylcarbamoyl)amino]naphthalene-1-sulfonyl chloride; 5-(N',N'-Dimethylureido)naphthalene-1-sulfonyl chloride; N,N-Dimethyl-N'-(1-sulfonylchloridenaphthalen-5-yl)urea; 728864-94-6; 5-(3,3-Dimethylureido)naphthalene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(3,3-Dimethyl-Ureido)-Naphthalene-1-Sulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical research and development processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.