Description

5-Propionylamino-Naphthalene-1-Sulfonyl Chloride is a specialized organic intermediate featuring a reactive sulfonyl chloride group and a propionylamino substituent on a naphthalene core. This compound matters as a critical building block for synthesizing complex molecules, particularly in the development of dyes, fluorescent probes, and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the fine chemical, pharmaceutical, and agrochemical industries for creating advanced functional materials and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors.
• Fluorescent Dye & Probe Synthesis: Used to create naphthalene-based fluorescent tags and sensors for biological imaging and diagnostic applications.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or plant growth regulators with tailored properties.
• Polymer & Material Science: Employed in the modification of polymers or surfaces to introduce specific functional groups for advanced material properties.
• Chemical Biology Tool Development: Utilized in creating affinity labels or activity-based probes for studying protein function and interactions.
• Academic & Industrial R&D: Fundamental reagent for organic synthesis research and process development in fine chemical production.

Basic Information

Product Name	5-Propionylamino-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-92-4
Molecular Formula	C₁₃H₁₂ClNO₃S
Molecular Weight	297.76 g/mol
Synonyms	5-Propionamidonaphthalene-1-sulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-(propionylamino)-; 5-Propionylamino-1-naphthalenesulfonyl chloride; N-(1-Sulfonylchloridenaphthalen-5-yl)propionamide; 5-Propionylaminonaphthalene-1-sulfonyl chloride; PNSC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Propionylamino-Naphthalene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability to minimize degradation from moisture and air.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.