Description

5-(3-Oxo-3-Phenyl-Propenyl)-Thiophene-2-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile electrophilic intermediate for introducing the thiophene sulfonamide moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active molecules, including potential kinase inhibitors and receptor antagonists.
• Agrochemical Research: Used to construct novel sulfonamide-based herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating functional polymers and advanced organic electronic materials.
• Chemical Biology: Employed in the development of activity-based probes and covalent inhibitors for protein labeling and study.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical suppliers for bespoke compound libraries.

Basic Information

Product Name	5-(3-Oxo-3-Phenyl-Propenyl)-Thiophene-2-Sulfonyl Chloride
CAS No.	728864-91-3
Molecular Formula	C14H9ClO3S2
Molecular Weight	324.80 g/mol
Synonyms	5-[(1E)-3-Oxo-3-phenyl-1-propen-1-yl]-2-thiophenesulfonyl chloride; 5-(3-Oxo-3-phenylpropenyl)thiophene-2-sulfonyl chloride; 2-Thiophenesulfonyl chloride, 5-[(1E)-3-oxo-3-phenyl-1-propenyl]-; (E)-5-(3-Oxo-3-phenylprop-1-en-1-yl)thiophene-2-sulfonyl chloride; 5-(3-Oxo-3-phenyl-acryloyl)-thiophene-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-(3-Oxo-3-Phenyl-Propenyl)-Thiophene-2-Sulfonyl Chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is fully characterized and undergoes rigorous analytical testing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.