Description

5-Ethylamino-Naphthalene-1-Sulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in organic synthesis. This compound is valued for its role as a versatile building block, enabling the introduction of the sulfonamide functional group into target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fluorescent probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides that utilize sulfonamide chemistry for enhanced activity.
• Fluorescent Labeling Reagent: Serves as a reactive moiety for labeling amines in proteins, peptides, and other biomolecules for analytical and diagnostic applications.
• Material Science Research: Employed in the creation of functionalized polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Utilized to develop activity-based probes for studying enzyme function and metabolic pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific sulfonylation reactions.

Basic Information

Product Name	5-Ethylamino-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-90-2
Molecular Formula	C₁₂H₁₂ClNO₂S
Molecular Weight	269.75 g/mol
Synonyms	5-(Ethylamino)naphthalene-1-sulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-(ethylamino)-; N-Ethyl-5-amino-1-naphthalenesulfonyl chloride; 5-Ethylaminonaphthalene-1-sulfonyl chloride; ENS-Cl
EINECS	Contact for details

Quality Control

Our 5-Ethylamino-Naphthalene-1-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (DMF, DMSO, acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.