Description

5-(Acetyl-Ethyl-Amino)-Naphthalene-1-Sulfonyl Chloride is a specialized organic intermediate featuring a reactive sulfonyl chloride group and a naphthalene-based fluorophore core. This compound is critical for the synthesis of advanced fluorescent probes and labeling reagents used in biochemical and diagnostic applications. It is primarily utilized by research institutions and manufacturers in the life sciences, pharmaceutical development, and analytical chemistry sectors seeking to create sensitive detection systems.

Application

• Synthesis of Fluorescent Dyes and Probes: Acts as a key precursor for creating sulfonamide-based fluorescent labels, such as dansyl chloride analogs, for protein and amino acid labeling.
• Bioconjugation Reagent Manufacturing: Used to produce reactive intermediates that covalently attach fluorophores to antibodies, peptides, or other biomolecules for imaging and assay development.
• Development of Diagnostic Assays: Serves as a building block for fluorescent tags in ELISA, fluorescence immunoassays (FIA), and other clinical diagnostic kits.
• Research Chemical for Sensor Development: Employed in academic and industrial R&D to design novel chemical sensors and molecular probes for detecting metal ions or small molecules.
• Pharmaceutical Intermediate: May be used in the research phase for synthesizing drug candidates where a naphthalene-sulfonamide scaffold is required.
• Material Science Applications: Potential use in the synthesis of functional polymers or organic electronic materials requiring specific light-absorbing/emitting properties.

Basic Information

Product Name	5-(Acetyl-Ethyl-Amino)-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-89-9
Molecular Formula	C₁₄H₁₄ClNO₃S
Molecular Weight	311.78 g/mol
Synonyms	5-(Acetylethylamino)naphthalene-1-sulfonyl chloride; 1-(N-Ethyl-N-acetylamino)-5-naphthalenesulfonyl chloride; N-Ethyl-N-(1-sulfo-5-naphthyl)acetamide chloride; AEANS-Cl; 5-(N-Ethylacetamido)-1-naphthalenesulfonyl chloride; Dansyl chloride derivative; 5-Acetylethylaminonaphthalene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-(Acetyl-Ethyl-Amino)-Naphthalene-1-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our processes are designed to meet the exacting standards of the fine chemical and life science industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., DMF, DMSO, acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.