Description

5-[(2-Ethyl-Piperidine-1-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride is a specialized organic intermediate featuring a reactive sulfonyl chloride group and a piperidine-based amide linkage. This compound is of significant value for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel chemical entities, such as protease inhibitors or other biologically active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting enzymatic pathways.
• Protease Inhibitor Development: Used in medicinal chemistry for constructing potential inhibitors where the sulfonamide moiety is a key pharmacophore.
• Chemical Biology Probes: Serves as a reagent for labeling or modifying biomolecules due to the reactivity of the sulfonyl chloride group with amines and alcohols.
• Agrochemical Research: Employed in the discovery and development of new crop protection agents with novel modes of action.
• Material Science: Can be utilized in the synthesis of specialty polymers or functionalized surfaces requiring specific aromatic sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-[(2-Ethyl-Piperidine-1-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-85-5
Molecular Formula	C18H21ClN2O3S
Molecular Weight	380.89 g/mol
Synonyms	1-Naphthalenesulfonyl chloride, 5-[[(2-ethyl-1-piperidinyl)carbonyl]amino]-; 5-[(2-Ethylpiperidine-1-carbonyl)amino]naphthalene-1-sulfonyl chloride; 5-Amino-1-naphthalenesulfonyl chloride derivative; N-(1-Sulfonylnaphthalen-5-yl)-2-ethylpiperidine-1-carboxamide; 728864-85-5; 5-[(2-Ethyl-piperidine-1-carbonyl)-amino]-naphthalene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-[(2-Ethyl-Piperidine-1-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.