Description

5-[(2,2-Dimethyl-Propionyl)-Ethyl-Amino]-Naphthalene-1-Sulfonyl Chloride is a specialized organic intermediate featuring a reactive sulfonyl chloride group and a protected amine moiety. This compound is critical for researchers and manufacturers requiring high-purity building blocks for the synthesis of complex molecules, particularly in advanced material and pharmaceutical development. It is primarily utilized in the production of fluorescent probes, dyes, and active pharmaceutical ingredients (APIs) where precise functionalization is essential.

Application

• Fluorescent Dye & Probe Synthesis: A key precursor for creating naphthalene-based fluorescent labels and sensors used in bioimaging and diagnostic assays.
• Pharmaceutical Intermediate: Serves as a versatile building block in the synthesis of novel drug candidates, especially those targeting specific enzymes or receptors.
• Polymer & Material Science: Used to functionalize polymers and surfaces, imparting specific chemical or luminescent properties to advanced materials.
• Chemical Research & Development: An essential reagent for academic and industrial R&D in organic chemistry, enabling the exploration of new sulfonamide and amide linkages.
• Agrochemical Synthesis: Employed in the development of new crop protection agents and herbicides that require sulfonamide-based active ingredients.

Basic Information

Product Name	5-[(2,2-Dimethyl-Propionyl)-Ethyl-Amino]-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-79-7
Molecular Formula	C₁₇H₂₀ClNO₃S
Molecular Weight	353.86 g/mol
Synonyms	5-[(2,2-Dimethylpropanoyl)(ethyl)amino]naphthalene-1-sulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-[(2,2-dimethyl-1-oxopropyl)ethylamino]-; N-Ethyl-5-(pivaloylamino)-1-naphthalenesulfonyl chloride; 5-(N-Ethylpivalamido)-1-naphthalenesulfonyl chloride; Piv-EDANS Sulfonyl Chloride; Piv-EDANS-Cl; 5-(N-Ethyl-2,2-dimethylpropanamido)naphthalene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-[(2,2-Dimethyl-Propionyl)-Ethyl-Amino]-Naphthalene-1-Sulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.