Description

5-(3,3-Dipropyl-Ureido)-Naphthalene-1-Sulfonyl Chloride is a specialized organic intermediate featuring a reactive sulfonyl chloride group and a ureido linker. This compound is of significant value for the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel chemical entities and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting enzyme inhibition or receptor modulation.
• Proteomics Research: Used in the development of chemical probes and activity-based protein profiling (ABPP) reagents due to its sulfonyl chloride reactivity.
• Peptide & Protein Modification: Acts as a derivatization agent for labeling amino acid residues like lysine or tyrosine in peptides and proteins.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialized polymers and functional surfaces.
• Chemical Biology Tool: Employed in the design of covalent inhibitors and affinity tags for studying biological pathways.
• Fine Chemical Synthesis: Intermediate in multi-step organic syntheses for producing dyes, sensors, and other high-value specialty chemicals.

Basic Information

Product Name	5-(3,3-Dipropyl-Ureido)-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-77-5
Molecular Formula	C20H25ClN2O3S
Molecular Weight	408.94 g/mol
Synonyms	5-(3,3-Dipropylureido)naphthalene-1-sulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-[[(dipropylamino)carbonyl]amino]-; N1-(3,3-Dipropylureido)naphthalene-5-sulfonyl chloride; 5-[(Dipropylcarbamoyl)amino]naphthalene-1-sulfonyl chloride; 5-(N,N-Dipropylureido)-1-naphthalenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-(3,3-Dipropyl-Ureido)-Naphthalene-1-Sulfonyl Chloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and custom purity grades or analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical: 97-99%)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (DCM, DMF, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.