Description

3-[3-(4-Chloro-Phenyl)-3-Oxo-Propenyl]-4-Methoxy-Benzenesulfonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive sulfonyl chloride and chalcone-like structural motifs. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry where it serves as a versatile building block for creating targeted bioactive agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, particularly those targeting specific enzymes or receptors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile electrophile in organic synthesis for constructing complex sulfonamide and sulfonate ester derivatives.
• Material Science: Potential building block for the development of specialty polymers and functional materials with specific surface properties.
• Bioconjugation Chemistry: The reactive sulfonyl chloride group enables its use in modifying proteins, peptides, and other biomolecules for research applications.

Basic Information

Product Name	3-[3-(4-Chloro-Phenyl)-3-Oxo-Propenyl]-4-Methoxy-Benzenesulfonyl Chloride
CAS No.	728864-71-9
Molecular Formula	C16H12Cl2O4S
Molecular Weight	371.24 g/mol
Synonyms	4-Methoxy-3-[3-(4-chlorophenyl)-3-oxoprop-1-en-1-yl]benzenesulfonyl chloride; 3-(3-(4-Chlorophenyl)-3-oxoprop-1-en-1-yl)-4-methoxybenzenesulfonyl chloride; 1-(4-Chlorophenyl)-3-(2-methoxy-5-(chlorosulfonyl)phenyl)prop-2-en-1-one; (E)-3-(4-Chlorophenyl)-1-[2-methoxy-5-(chlorosulfonyl)phenyl]prop-2-en-1-one; 3-(3-(4-Chloro-phenyl)-3-oxo-propenyl)-4-methoxy-benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-[3-(4-Chloro-Phenyl)-3-Oxo-Propenyl]-4-Methoxy-Benzenesulfonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. The material is manufactured and tested in facilities that follow cGMP principles where applicable. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.