Description

4-[(3-Methyl-Piperidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual functional groups, enabling its use as a key intermediate in the development of pharmacologically active molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting protease or kinase enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Biology Probes: Employed in the development of activity-based probes for studying biological pathways and target engagement.
• Peptidomimetic Synthesis: Serves as a coupling agent or core scaffold in the construction of peptidomimetic compounds.
• Agrochemical Development: Potential intermediate in the research and development of new crop protection agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-[(3-Methyl-Piperidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride
CAS No.	728864-64-0
Molecular Formula	C14H19ClN2O3S
Molecular Weight	330.83 g/mol
Synonyms	4-[(3-Methylpiperidine-1-carbonyl)amino]benzenesulfonyl chloride; 4-[(3-Methyl-1-piperidinyl)carbonyl]amino]benzenesulfonyl chloride; 3-Methyl-1-[(4-(chlorosulfonyl)phenyl)carbamoyl]piperidine; Benzenesulfonyl chloride, 4-[[(3-methyl-1-piperidinyl)carbonyl]amino]-; 728864-64-0; 4-(3-Methylpiperidine-1-carboxamido)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-[(3-Methyl-Piperidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.