Description

(4-(3-(Aminomethyl)Phenyl)Piperidin-1-Yl)(5-((2-Fluorophenyl)Ethynyl)Furan-2-Yl)Methanone Methanesulfonate is a high-purity, non-racemic pharmaceutical intermediate and research chemical of significant interest in modern drug discovery. Its complex molecular architecture, featuring a piperidine core linked to a fluorinated aryl ethynyl furan moiety, makes it a valuable building block for synthesizing novel bioactive compounds. This product is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the research and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D laboratories.
• Process Chemistry & Scale-Up: Used in route development and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Employed in pharmacological assays to study receptor interactions and enzyme inhibition mechanisms.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Custom Synthesis Building Block: Provides a versatile chiral starting material for contract research organizations (CROs) and custom synthesis providers.

Basic Information

Product Name	(4-(3-(Aminomethyl)Phenyl)Piperidin-1-Yl)(5-((2-Fluorophenyl)Ethynyl)Furan-2-Yl)Methanone Methanesulfonate
CAS No.	725228-55-7
Molecular Formula	C26H25FN2O2 • CH4O3S
Molecular Weight	488.56 g/mol
Synonyms	Methanone, [4-[3-(aminomethyl)phenyl]-1-piperidinyl][5-[(2-fluorophenyl)ethynyl]-2-furanyl]-, methanesulfonate (1:1); UNII-3X4R8K213K; 3X4R8K213K; (4-(3-(Aminomethyl)phenyl)piperidin-1-yl)(5-((2-fluorophenyl)ethynyl)furan-2-yl)methanone methanesulfonate; 725228-55-7; Methanesulfonic acid compound with [4-[3-(aminomethyl)phenyl]-1-piperidinyl][5-[(2-fluorophenyl)ethynyl]-2-furanyl]methanone (1:1)
EINECS	Contact for details

Quality Control

Our production of (4-(3-(Aminomethyl)Phenyl)Piperidin-1-Yl)(5-((2-Fluorophenyl)Ethynyl)Furan-2-Yl)Methanone Methanesulfonate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.