Description

Adenosine-3'-13C CAS NO 714950-53-5 is a stable isotope-labeled analog of adenosine, a fundamental nucleoside in biochemistry. This product is essential for advanced research and development, providing a critical tool for metabolic pathway tracing and quantitative analysis via mass spectrometry. It is primarily required by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) studies, proteomics, and biomarker discovery.

Application

• Isotope-Labeled Internal Standards: For precise quantification of adenosine and its metabolites in biological samples using LC-MS/MS.
• Drug Metabolism Studies (DMPK): Tracing the metabolic fate of nucleoside-based pharmaceuticals to identify metabolites and understand clearance pathways.
• Biochemical Pathway Analysis: Investigating purine metabolism, ATP/ADP/AMP cycling, and energy charge in cellular systems.
• Proteomics and Biomarker Research: Used in stable isotope labeling by amino acids in cell culture (SILAC) or other labeling techniques for protein turnover studies.
• NMR Spectroscopy: Serving as a 13C-enriched standard for structural elucidation and dynamic studies of nucleic acids and related compounds.
• Enzyme Kinetics: As a substrate for studying the activity and inhibition of kinases, adenosine deaminase, and other nucleoside-modifying enzymes.

Basic Information

Product Name	Adenosine-3'-13C
CAS No.	714950-53-5
Molecular Formula	C10H12N5O4 (with 13C at the 3' position)
Molecular Weight	Contact for details
Synonyms	3'-13C-Adenosine; Adenosine (3'-13C); 9-β-D-Ribofuranosyladenine-3'-13C; 6-Amino-9-β-D-ribofuranosyl-9H-purine-3'-13C; 13C Labeled Adenosine; [3'-13C]Adenosine; Stable Isotope Labeled Adenosine; Adenosine-13C (partial labeling specifier)
EINECS	Contact for details

Quality Control

Every batch of Adenosine-3'-13C is produced and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including HPLC for chemical purity, NMR and/or MS for isotopic enrichment verification, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to expected mass
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C (at 3' position)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.