Description

4-Bromobenzeneethanesulfonyl Chloride is a versatile and reactive organosulfur compound, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality, acting as a sulfonylating agent and providing a brominated aromatic handle for subsequent cross-coupling reactions. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with sulfonyl functional groups.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Acts as a reagent for labeling and modifying biomolecules to study protein function and interactions.
• Cross-Coupling Reactions: The bromoaryl moiety facilitates Suzuki, Stille, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Sulfonylation Agent: Used to introduce the ethanesulfonyl chloride group into target molecules, a common pharmacophore.

Basic Information

Product Name	4-Bromobenzeneethanesulfonyl Chloride
CAS No.	711018-68-7
Molecular Formula	C8H8BrClO2S
Molecular Weight	283.57 g/mol
Synonyms	2-(4-Bromophenyl)ethanesulfonyl chloride; 4-Bromophenethylsulfonyl chloride; p-Bromophenethylsulfonyl chloride; 1-Bromo-4-(2-chlorosulfonylethyl)benzene; 4-Bromo-β-phenylethanesulfonyl chloride; (4-Bromophenyl)ethanesulfonyl chloride; 2-(4-Bromophenyl)-1-ethanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromobenzeneethanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.