Description

Gsk-3 Inhibitor Ix, Control, Mebio is a high-purity, small-molecule reference standard specifically designed for research and development applications. This compound serves as a critical tool for the study of glycogen synthase kinase-3 (GSK-3) signaling pathways, which are implicated in numerous biological processes. It is essential for scientists in pharmaceutical discovery, academic research, and biotechnology who require reliable, well-characterized biochemical tools for target validation, assay development, and mechanistic studies.

Application

• Biochemical Research: Used as a selective inhibitor in enzymatic assays to study the role of GSK-3 in cellular signaling cascades.
• Pharmaceutical R&D: Serves as a reference compound and positive control in high-throughput screening (HTS) campaigns for drug discovery targeting GSK-3.
• Cell Biology Studies: Applied in cell-based experiments to investigate the effects of GSK-3 inhibition on processes such as metabolism, proliferation, and gene expression.
• Neuroscience Research: Utilized in models studying neurodegenerative diseases, where GSK-3 activity is a key pathological factor.
• Oncology Research: Employed to explore the therapeutic potential of GSK-3 inhibition in various cancer cell lines and animal models.
• Quality Control: Acts as a system suitability standard and control material in analytical method development and validation within QC laboratories.

Basic Information

Product Name	Gsk-3 Inhibitor Ix, Control, Mebio
CAS No.	710323-61-8
Molecular Formula	C16H12N4O2S
Molecular Weight	324.36 g/mol
Synonyms	GSK-3 Inhibitor IX; GSK-3 Inhibitor Ix, Control; 6-Bromoindirubin-3'-oxime (BIO); (2'Z,3'E)-6-Bromoindirubin-3'-oxime; BIO; 6-Bromoindirubin-3'-oxime; Axon 1386; Mebio Control Compound
EINECS	Contact for details

Quality Control

Our Gsk-3 Inhibitor Ix, Control, Mebio is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.