Description

5H-Dibenz(D,F)Azonin-1-Ol, 6,7,8,9-Tetrahydro-2,12-Dimethoxy-7-Methyl- 6-(Phenylmethyl)-, Acetate (Ester), (-)- is a high-purity, complex organic compound with a defined stereochemistry, serving as a critical advanced intermediate in pharmaceutical research and development. Its intricate polycyclic structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) and for use in medicinal chemistry studies. This compound is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical suppliers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and neurological research.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic compounds.
• Reference Standard: Serves as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Research: Potential use as a tool compound in pharmacological assays and for studying specific biological pathways and receptor interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	5H-Dibenz(D,F)Azonin-1-Ol, 6,7,8,9-Tetrahydro-2,12-Dimethoxy-7-Methyl- 6-(Phenylmethyl)-, Acetate (Ester), (-)-
CAS No.	79989-25-6
Molecular Formula	C27H29NO4
Molecular Weight	431.52 g/mol
Synonyms	(-)-6-Benzyl-2,12-dimethoxy-7-methyl-6,7,8,9-tetrahydro-5H-dibenzo[d,f]azonin-1-yl acetate; 6-Benzyl-2,12-dimethoxy-7-methyl-6,7,8,9-tetrahydro-5H-dibenzo[d,f]azonin-1-ol acetate (ester), (-)-; 79989-25-6; UNII-2J3R8D1Q8F; 2J3R8D1Q8F; SCHEMBL21824027; DTXSID40422323
EINECS	Contact for details

Quality Control

Our 5H-Dibenz(D,F)Azonin-1-Ol, 6,7,8,9-Tetrahydro-2,12-Dimethoxy-7-Methyl- 6-(Phenylmethyl)-, Acetate (Ester), (-)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.