Description

Castanospermine is a potent and specific indolizidine alkaloid glycosidase inhibitor, widely recognized for its unique biochemical activity. This compound is a critical research tool for studying carbohydrate-processing enzymes and their role in various biological pathways. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for drug discovery and biochemical mechanism studies. The compound is supplied under the identifier CAS NO 79831-76-8.

Application

• Biochemical Research: As a standard inhibitor for α-glucosidase I and other glycosidases in enzymatic studies.
• Virology Studies: Investigation of antiviral agents, particularly for its potential to inhibit the maturation of viral envelope glycoproteins.
• Metabolic Disorder Research: Used in models for studying lysosomal storage diseases and diabetes.
• Glycobiology: A key reagent for probing N-linked oligosaccharide processing and glycoprotein function.
• Pharmaceutical Development: Serves as a lead compound or pharmacophore for designing novel therapeutic agents targeting glycosidase enzymes.
• Cell Biology: Tool for studying endoplasmic reticulum (ER) quality control and protein trafficking.

Basic Information

Product Name	Castanospermine
CAS No.	79831-76-8
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	1,6,7,8-Tetrahydroxyoctahydroindolizine; (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine; NSC 329853; Castanospermin; 6-O-α-Glucosidase inhibitor; Alexine isomer; (+)-Castanospermine
EINECS	Contact for details

Quality Control

Our Castanospermine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	+75° to +85° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.