Description

7-Oxoprostaglandin I2 is a stable, biologically active metabolite of prostacyclin (PGI2) with significant research and pharmaceutical interest. This compound serves as a crucial reference standard and synthetic intermediate for studying cardiovascular and pulmonary physiology, particularly related to platelet aggregation and vasodilation. It is essential for researchers and developers in the pharmaceutical, biotechnology, and advanced life science sectors who require high-purity biochemical tools for drug discovery and metabolic pathway analysis.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of prostacyclin metabolites in drug development and bioanalytical research.
• Biochemical Research: A key tool for investigating the role of prostanoids in vascular biology, inflammation, and cell signaling pathways.
• Drug Discovery Intermediate: Serves as a critical synthetic building block for the development of novel cardiovascular and anti-thrombotic therapeutics.
• Metabolite Studies: Employed in metabolic stability studies and pharmacokinetic profiling of prostacyclin analogs.
• In Vitro Diagnostics: Used in the calibration and validation of diagnostic assays measuring eicosanoid levels in biological samples.

Basic Information

Product Name	7-Oxoprostaglandin I2
CAS No.	79821-50-4
Molecular Formula	C₂₀H₃₂O₆
Molecular Weight	368.47 g/mol
Synonyms	7-Oxo-PGI2; 7-Ketoprostacyclin; 7-Oxo-prostacyclin; 15-Deoxy-13,14-dihydro-15-oxo-PGI2; 7-Oxo-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid; 7-Oxo-PGI2 sodium salt (derivative); 15-Deoxy-δ¹²,¹⁴-PGJ2 analog
EINECS	Contact for details

Quality Control

Our 7-Oxoprostaglandin I2 is manufactured under strict quality management systems to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods including HPLC and spectroscopic techniques. We adhere to relevant guidelines for the production of fine chemicals for research use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.