Description

(2R,4Aβ,8Aα)-8α-[4-(1,1-Dimethylheptyl)-2-Hydroxyphenyl]Decahydro-6α-Hydroxy-2α-Naphthalenemethanol is a high-purity, stereochemically defined synthetic cannabinoid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical reference standard and a key synthetic intermediate for investigating cannabinoid receptor pharmacology and developing novel therapeutic agents. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise, high-quality building blocks for drug discovery programs.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for quality control and method validation in the development of cannabinoid-based therapeutics.
• Drug Discovery Intermediate: Acts as a crucial synthetic building block for the research and development of novel cannabinoid receptor (CB1/CB2) agonists, antagonists, and modulators.
• Biochemical Research: Used in in vitro and in vivo studies to elucidate the structure-activity relationships (SAR) and metabolic pathways of synthetic cannabinoids.
• Process Chemistry & Scale-up: Employed as a starting material or intermediate in the pilot-scale and commercial-scale synthesis of active pharmaceutical ingredients (APIs).
• Analytical Method Development: Utilized to develop and calibrate advanced analytical techniques such as HPLC, LC-MS, and NMR for cannabinoid analysis.

Basic Information

Product Name	(2R,4Aβ,8Aα)-8α-[4-(1,1-Dimethylheptyl)-2-Hydroxyphenyl]Decahydro-6α-Hydroxy-2α-Naphthalenemethanol
CAS No.	79732-52-8
Molecular Formula	C25H40O3
Molecular Weight	388.59 g/mol
Synonyms	8α-Hydroxy-δ9-THC; 8α-Hydroxy-δ9-Tetrahydrocannabinol; 8α-OH-δ9-THC; (2R,4aR,8aR)-8a-[4-(1,1-Dimethylheptyl)-2-hydroxyphenyl]decahydro-6a-hydroxy-2-naphthalenemethanol; 8α-Hydroxy-δ9-trans-Tetrahydrocannabinol; 8α-Hydroxy-trans-δ9-THC; 8α-Hydroxy-trans-Tetrahydrocannabinol
EINECS	Contact for details

Quality Control

Our (2R,4Aβ,8Aα)-8α-[4-(1,1-Dimethylheptyl)-2-Hydroxyphenyl]Decahydro-6α-Hydroxy-2α-Naphthalenemethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.