Description

19-Hydroxy-5,8,11,14-Eicosatetraenoic Acid is a hydroxylated derivative of arachidonic acid, belonging to the class of eicosanoids. This compound serves as a key intermediate and reference standard in the study of lipid metabolism and inflammatory pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery, biochemical research, and analytical method development.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in the study of eicosanoid biosynthesis, metabolism, and signaling pathways.
• Pharmaceutical Development: Serves as a key starting material or analytical standard in the research and development of anti-inflammatory drugs and other therapeutics targeting lipid mediators.
• Cell Signaling Studies: Employed in in vitro and in vivo studies to investigate the role of hydroxyeicosatetraenoic acids (HETEs) in cellular processes.
• Analytical Chemistry: Used as a high-purity standard for method validation in analytical techniques such as HPLC, LC-MS, and GC-MS for lipidomic profiling.
• Enzymology: Acts as a substrate or product in assays for enzymes like cytochrome P450s, lipoxygenases, and cyclooxygenases.

Basic Information

Product Name	19-Hydroxy-5,8,11,14-Eicosatetraenoic Acid
CAS No.	79551-85-2
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	19-HETE; 19-Hydroxyarachidonic Acid; 19-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 19(S)-HETE; 19(R)-HETE; (±)19-HETE; 19-Hydroxy-AA
EINECS	Contact for details

Quality Control

Our 19-Hydroxy-5,8,11,14-Eicosatetraenoic Acid is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing specific results for purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.