Description

Menthol Glucuronide is a key metabolite of menthol, formed via glucuronidation in the liver. This compound is of significant interest for its role in pharmacokinetic and metabolic studies, providing crucial data on the biotransformation and clearance pathways of menthol. It serves as an essential analytical reference standard for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and flavor & fragrance industries, enabling precise quantification and metabolic profiling.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for bioanalytical method development and validation in drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolite Identification & Quantification: Critical for in-vitro and in-vivo studies to track and quantify the primary Phase II metabolite of menthol.
• Toxicological Research: Employed in safety and toxicology assessments to understand the excretion profile and potential bioactivity of menthol metabolites.
• Flavor & Fragrance Analysis: Supports research into the metabolic fate and regulatory safety profiling of menthol used in food, oral care, and cosmetic products.
• Clinical Diagnostics: Can be utilized in developing diagnostic assays to monitor menthol exposure or metabolism in clinical settings.
• Academic Research: A vital tool for universities and research institutes studying glucuronidation pathways, enzyme kinetics, and metabolic engineering.

Basic Information

Product Name	Menthol Glucuronide
CAS No.	79466-08-3
Molecular Formula	C₁₆H₂₈O₇
Molecular Weight	332.39 g/mol
Synonyms	(-)-Menthol glucuronide; L-Menthol glucuronide; Menthol β-D-glucuronide; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl β-D-Glucopyranosiduronic Acid; 5-Methyl-2-(1-methylethyl)cyclohexyl β-D-Glucopyranosiduronic Acid; p-Menth-3-ol glucuronide; Menthol glucuronide metabolite
EINECS	Contact for details

Quality Control

Our Menthol Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material at -20°C to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.