Description

2,4,6-Trifluorotoluene CAS NO 79348-71-3 is a versatile fluorinated aromatic building block prized for its unique electronic and steric properties. This compound is critical for introducing fluorine atoms into complex molecular architectures, significantly altering their reactivity, stability, and bioavailability. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and thermal stability.
• Polymer & Resin Modifier: Employed to introduce fluorine into polymer backbones or side chains, enhancing chemical resistance, reducing surface energy, and improving weatherability.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution due to the activated fluorine atoms on the benzene ring.
• Specialty Solvent & Reagent: Functions as a unique solvent in specific fluorination reactions or as a reagent in the preparation of more complex fluorinated compounds.

Basic Information

Product Name	2,4,6-Trifluorotoluene
CAS No.	79348-71-3
Molecular Formula	C7H5F3
Molecular Weight	146.11 g/mol
Synonyms	1,3,5-Trifluoro-2-methylbenzene; α,α,α-Trifluoro-2,4,6-trimethylbenzene (incorrect but common); Toluene, 2,4,6-trifluoro-; 2-Methyl-1,3,5-trifluorobenzene; 2,4,6-Trifluoromethylbenzene (common misnomer); 2,4,6-Trifluoro-1-methylbenzene
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluorotoluene is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are properly sealed. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.25 g/cm³
Boiling Point	~142-145 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.