Description

11-Dehydro-13,14-Dihydro-15-Keto-Thromboxane B2 is a stable metabolite and analog of thromboxane B2, a key eicosanoid involved in platelet aggregation and vascular function. This compound serves as a critical reference standard and analytical tool for research into thromboxane pathways and related physiological processes. It is primarily utilized by pharmaceutical researchers, clinical diagnostic developers, and academic institutions focused on cardiovascular biology, inflammation, and eicosanoid metabolism.

Application

• Biomedical Research Standard: Used as a high-purity reference standard in analytical methods like LC-MS/MS and ELISA for quantifying thromboxane metabolites in biological samples.
• Cardiovascular & Inflammation Studies: Essential for investigating the role of thromboxane in platelet activation, vasoconstriction, and inflammatory responses in preclinical research.
• Diagnostic Assay Development: Serves as a critical calibrator and quality control material in the development and validation of clinical diagnostic kits for eicosanoid profiling.
• Pharmaceutical R&D: Employed in drug discovery programs targeting thromboxane synthase or the thromboxane receptor (TP receptor) to screen potential inhibitors or modulators.
• Metabolomics & Biomarker Discovery: A key analyte in metabolomic studies aiming to identify and validate thromboxane-related biomarkers for various disease states.

Basic Information

Product Name	11-Dehydro-13,14-Dihydro-15-Keto-Thromboxane B2
CAS No.	79250-58-1
Molecular Formula	C20H32O6
Molecular Weight	368.47 g/mol
Synonyms	11-Dehydro-13,14-dihydro-15-keto-TXB2; 11-Dehydro-13,14-dihydro-15-ketothromboxane B2; 15-Keto-13,14-dihydro-11-dehydro-thromboxane B2; DHK-TXB2; 11-Dehydro-13,14-dihydro-15-oxo-thromboxane B2; Thromboxane B2 Metabolite; TXB2 Metabolite
EINECS	Contact for details

Quality Control

Our 11-Dehydro-13,14-Dihydro-15-Keto-Thromboxane B2 is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-controlled environment. The product is hygroscopic and light-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.