Description

n-Dodecyldeoxynojirimycin is a potent and selective alkylated iminosugar derivative, widely recognized for its role as a pharmacological chaperone and α-glucosidase inhibitor. This compound is critical for research and development in addressing protein misfolding disorders and modulating glycosidase activity. It is primarily utilized by pharmaceutical researchers, biochemists, and process development scientists working on advanced therapeutics, enzyme mechanism studies, and high-purity reference standards.

Application

• Pharmacological Chaperone Therapy: Investigational use in lysosomal storage diseases, such as Gaucher's disease and Fabry disease, to stabilize mutant enzyme structures and enhance cellular trafficking.
• Glycosidase Inhibition Research: Serves as a key biochemical tool for studying the mechanisms of α-glucosidases in metabolic pathways.
• Antiviral Research: Exploration of activity against viruses like HIV and hepatitis B that utilize host glycosylation pathways.
• Reference Standard: High-purity material for use in analytical method development, validation, and quality control within pharmaceutical laboratories.
• Process Chemistry & Intermediate: Used in the synthesis of more complex therapeutic molecules or diagnostic agents.
• Academic & Institutional Research: Fundamental research in glycobiology, cell biology, and medicinal chemistry.

Basic Information

Product Name	n-Dodecyldeoxynojirimycin
CAS No.	79206-22-7
Molecular Formula	C18H37NO4
Molecular Weight	331.50 g/mol
Synonyms	N-Dodecyl-1,5-dideoxy-1,5-imino-D-glucitol; N-Dodecyl-DNJ; Dodecyl-DNJ; DD-DNJ; N-Dodecyl-1-deoxynojirimycin; 1-Dodecyldeoxynojirimycin; N-Lauryl-deoxynojirimycin; (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-dodecylpiperidine-3,4,5-triol
EINECS	Contact for details

Quality Control

Our n-Dodecyldeoxynojirimycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.