Description

L-Ap5 CAS NO 79055-67-7 is a high-purity, synthetic amino acid derivative widely utilized in advanced biochemical research and pharmaceutical development. This compound is valued for its role as a selective and potent antagonist of glutamate receptors, particularly the NMDA subtype, making it a critical tool for neurological studies. It is primarily sought by researchers and manufacturers in the fields of neuroscience, pharmacology, and medicinal chemistry for investigating synaptic transmission, neurotoxicity, and developing potential therapeutic agents.

Application

• Neuroscience Research: As a selective NMDA receptor antagonist for studying excitatory synaptic transmission, long-term potentiation (LTP), and neuroplasticity.
• Pharmacological Studies: Used in vitro and in vivo to model neurological conditions and evaluate the efficacy of novel neuroprotective compounds.
• Biochemical Assay Development: Serves as a reference standard and key reagent in high-throughput screening assays targeting glutamate pathways.
• Medicinal Chemistry: Acts as a crucial building block or pharmacophore in the synthesis and design of new central nervous system (CNS) active drugs.
• Academic & Industrial R&D: Essential for basic research in university laboratories and for drug discovery pipelines in biopharmaceutical companies.

Basic Information

Item	Detail
Product Name	L-Ap5
CAS No.	79055-67-7
Molecular Formula	C5H10N2O5
Molecular Weight	178.15 g/mol
Synonyms	L-2-Amino-5-phosphonopentanoic acid; (S)-2-Amino-5-phosphonopentanoic acid; L-AP5; L-APV; (S)-AP5; NMDA receptor antagonist AP5; Abt-001; (S)-2-Amino-5-phosphonovaleric acid
EINECS	Contact for details

Quality Control

Every batch of L-Ap5 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with the standards expected for research-grade biochemicals, supporting reproducible and reliable scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.