Description

(3,3,4,4,4-D5)-(E/Z)-1-[4-(2-Chloroethoxy)Phenyl]-1-[4-Hydroxyphenyl]-2-Phenyl-1-Butene is a deuterated analog of a complex stilbene derivative, offering a valuable isotopically labeled building block for advanced research and development. This compound is critical for applications requiring precise metabolic and pharmacokinetic studies, where tracking molecular pathways is essential. It is primarily utilized by pharmaceutical researchers, analytical chemists, and material scientists working on high-performance organic electronic materials and novel therapeutic agents.

Application

• Deuterated Internal Standard for the quantitative analysis of its non-deuterated counterpart in complex biological matrices using LC-MS or GC-MS.
• Metabolic Tracing Studies in pharmaceutical R&D to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of drug candidates.
• Precursor for Advanced Materials, serving as a deuterated monomer in the synthesis of specialized polymers for optoelectronic devices.
• Mechanistic Research in organic chemistry, utilizing the kinetic isotope effect (KIE) to study reaction pathways and mechanisms.
• Reference Compound for method development and validation in regulatory and quality control laboratories.
• Synthesis of Labeled Probes for use in biomedical imaging and diagnostic assays.

Basic Information

Product Name	(3,3,4,4,4-D5)-(E/Z)-1-[4-(2-Chloroethoxy)Phenyl]-1-[4-Hydroxyphenyl]-2-Phenyl-1-Butene
CAS No.	78995-98-9
Molecular Formula	C24H19D5ClO3
Molecular Weight	~410.95 g/mol
Synonyms	Deuterated Tamoxifen Metabolite Analog; 1-[4-(2-Chloroethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenyl-1-butene-d5; (E/Z)-4-Hydroxytamoxifen D5 Chloroethyl Ether; 4-Hydroxy-N-desmethyltamoxifen D5 Chloroethyl Ether Derivative; Deuterated Stilbene Derivative; 1,1-Bis(4-hydroxyphenyl)-2-phenylbut-1-ene-d5 2-Chloroethyl Ether; [D5]-1-[4-(2-Chloroethoxy)Phenyl]-1-[4-Hydroxyphenyl]-2-Phenyl-1-Butene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, isotopic purity, and chemical purity. Certificates of Analysis (COA) detailing specific results for deuterium enrichment, isomeric ratio (E/Z), and impurity profiles are available upon request, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider handling under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Total of E and Z isomers)
Deuterium Enrichment (MS)	≥ 98 atom % D
Isomeric Ratio (E/Z)	Specified on COA
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.