Description

Benzenesulfonyl Chloride, 4-Amino-3-Chloro- CAS NO 78957-18-3 is a key halogenated and aminated benzenesulfonyl chloride derivative, serving as a versatile and reactive synthetic intermediate. Its value lies in its bifunctional nature, allowing for selective reactions at both the sulfonyl chloride and amino groups to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of sulfonamide-based drugs, including diuretics, carbonic anhydrase inhibitors, and antiviral agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, leveraging its reactivity to create novel active compounds.
• Dye and Pigment Manufacturing: Acts as a precursor for azo dyes and other colored compounds, where the amino and sulfonyl groups contribute to chromophore formation and solubility.
• Polymer Modification: Employed to introduce sulfonamide functional groups into polymer chains, enhancing properties like hydrophilicity or biological activity.
• Chemical Research & Development: Serves as a standard reagent in organic synthesis for constructing sulfonamide linkages and exploring new reaction pathways.
• Specialty Chemical Production: Utilized in the manufacture of surfactants, corrosion inhibitors, and other performance chemicals.

Basic Information

Product Name	Benzenesulfonyl Chloride, 4-Amino-3-Chloro- CAS NO 78957-18-3
CAS No.	78957-18-3
Molecular Formula	C6H5Cl2NO2S
Molecular Weight	226.08 g/mol
Synonyms	3-Chloro-4-aminobenzenesulfonyl chloride; 4-Amino-3-chlorobenzenesulfonyl chloride; 3-Chloro-4-aminobenzene-1-sulfonyl chloride; 1-Chlorosulfonyl-2-chloro-4-aminobenzene; 2-Chloro-4-aminobenzenesulfonyl chloride; 4-Amino-3-chlorophenylsulfonyl chloride; Benzenesulfonyl chloride, 4-amino-3-chloro-; (4-Amino-3-chlorophenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our Benzenesulfonyl Chloride, 4-Amino-3-Chloro- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.