Description

Iloprost is a synthetic analog of prostacyclin (PGI2), a potent vasodilator and inhibitor of platelet aggregation. This compound is of critical importance in pharmaceutical research and development, particularly for its therapeutic effects on vascular and pulmonary systems. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions developing treatments for pulmonary arterial hypertension (PAH) and other vascular disorders, as well as in biochemical studies of prostaglandin pathways.

Application

• Pharmaceutical Active Ingredient (API): Core component in medications for the treatment of pulmonary arterial hypertension (PAH).
• Vascular Research: Used in preclinical and clinical studies to investigate vasodilation, platelet function, and endothelial cell protection.
• Pulmonary Therapy Development: Key material in formulating inhalable or intravenous solutions for lung-targeted therapies.
• Cell Culture & Biochemistry: Employed as a research tool to study prostaglandin signaling pathways and their role in inflammation and vascular tone.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	Iloprost
CAS No.	78919-13-8
Molecular Formula	C₂₂H₃₂O₄
Molecular Weight	360.49 g/mol
Synonyms	ZK 36374; Ilomedin; 5-{(E)-(1S,5S,6R,7R)-7-Hydroxy-6-[(E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl]-bicyclo[3.3.0]octan-3-ylidene}pentanoic Acid; (E)-(3aS,4R,5R,6aS)-5-Hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-hexahydro-2H-cyclopenta[b]furan-2-ylidene)pentanoic Acid; Prostacyclin PGI2 analog; Cicaprost (related analog).
EINECS	Contact for details

Quality Control

Our Iloprost is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications suitable for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.