Description

3-Chloro-2-Nitrobenzenesulfonyl Chloride is a versatile and highly reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the sulfonyl chloride group acts as a powerful electrophile for sulfonamide formation and the nitro and chloro substituents offer sites for further selective chemical transformations. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that require a sulfonamide pharmacophore.
• Dyestuff and Pigment Manufacturing: Used in the production of specialty dyes and organic pigments, leveraging its aromatic nitro and sulfonyl chloride groups.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and high-performance materials.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for screening.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and catalysts used in asymmetric synthesis and metal-organic frameworks.

Basic Information

Product Name	3-Chloro-2-Nitrobenzenesulfonyl Chloride
CAS No.	78846-40-9
Molecular Formula	C6H3Cl2NO4S
Molecular Weight	256.06 g/mol
Synonyms	2-Nitro-3-chlorobenzenesulfonyl chloride; 3-Chloro-2-nitrobenzene-1-sulfonyl chloride; 1-Chloro-2-nitro-6-sulfonylchloridebenzene; Benzenesulfonyl chloride, 3-chloro-2-nitro-; 3-Chloro-2-nitrobenzenesulphonyl chloride; 2-Nitro-3-chlorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Nitrobenzenesulfonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and stored away from direct light sources.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.