Description

Acetanilide-Ring-Ul-14C is a carbon-14 labeled isotopologue of acetanilide, specifically radiolabeled on the aromatic ring. This compound is essential for advanced metabolic and pharmacokinetic studies, providing a critical tool for precise tracing of molecular pathways. It is primarily required by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors for applications in drug development and safety assessment.

Application

• Tracer Studies in Drug Metabolism: Used as a radiolabeled internal standard in LC-MS and HPLC analyses to quantify drug metabolites and study biotransformation pathways.
• Pharmacokinetic (PK) and Absorption, Distribution, Metabolism, and Excretion (ADME) Research: Enables precise tracking of a compound's fate within biological systems to determine bioavailability and clearance rates.
• Environmental Fate Studies: Applied in research to trace the degradation and persistence of chemical compounds in ecosystems.
• Biochemical Pathway Analysis: Serves as a probe in mechanistic studies to elucidate enzymatic reactions and metabolic routes.
• Reference Standard for Analytical Method Development: Used to validate and calibrate analytical methods (e.g., radio-HPLC) for specificity and sensitivity.
• Synthesis of Labeled Intermediates: Acts as a building block for the synthesis of more complex carbon-14 labeled compounds for research.

Basic Information

Product Name	Acetanilide-Ring-Ul-14C
CAS No.	78645-81-5
Molecular Formula	C8H914CON (or C814C1H9NO)
Molecular Weight	~136.15 g/mol (based on 14C substitution)
Synonyms	N-Phenylacetamide-UL-ring-14C; Acetanilide (ring-U-14C); N-Acetylaniline-UL-ring-14C; Antifebrin-14C; 14C-Acetanilide; [Ring-U-14C]Acetanilide; N-(Phenyl-UL-14C)acetamide; Acecanilidum-14C
EINECS	Contact for details

Quality Control

Every batch of Acetanilide-Ring-Ul-14C is produced and analyzed under strict quality protocols to ensure high chemical, radiochemical, and isotopic purity. Our quality assurance includes comprehensive testing via HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, specifying the exact radiochemical purity, specific activity, and analytical chromatograms.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at recommended temperatures (typically 2-8°C or as specified on the label). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. Handle and store in accordance with all local and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98% (Chemical)
Radiochemical Purity	≥ 97%
Specific Activity	Customizable (mCi/mmol)
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.