Description

3-Methyl-2-Oxo-2,3-Dihydro-1,3-Benzoxazole-5-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a key reactive intermediate in modern synthetic chemistry. Its primary value lies in its role as a versatile building block for introducing the sulfonamide moiety into target molecules, enabling the development of compounds with specific biological or material properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly those focused on creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonamide group confers specific biological activity.
• Dye and Pigment Manufacturing: Serves as a key reactant for producing sulfonated dyes and colorants with enhanced solubility and fastness properties.
• Polymer Modification: Employed to introduce sulfonyl chloride functional groups into polymer chains for subsequent cross-linking or to impart specific chemical reactivity.
• Chemical Research & Development: A valuable tool for medicinal and process chemists exploring new synthetic routes and creating compound libraries for screening.
• Ligand Synthesis for Catalysis: Used in the preparation of specialized ligands containing sulfonamide groups for metal-complex catalysts.

Basic Information

Product Name	3-Methyl-2-Oxo-2,3-Dihydro-1,3-Benzoxazole-5-Sulfonyl Chloride
CAS No.	78633-42-8
Molecular Formula	C8H6ClNO4S
Molecular Weight	247.66 g/mol
Synonyms	5-(Chlorosulfonyl)-3-methyl-1,3-benzoxazol-2(3H)-one; 3-Methyl-2-oxo-2,3-dihydrobenzoxazole-5-sulfonyl chloride; 3-Methyl-2-oxo-2H-1,3-benzoxazole-5-sulfonyl chloride; 3-Methyl-2-oxo-2,3-dihydrobenzo[d]oxazole-5-sulfonyl chloride; 3-Methyl-2-oxo-2,3-dihydrobenzoxazole-5-sulfonyl chloride; 1,3-Benzoxazol-2(3H)-one, 5-(chlorosulfonyl)-3-methyl-; 5-Chlorosulfonyl-3-methyl-2-benzoxazolinone
EINECS	Contact for details

Quality Control

Our 3-Methyl-2-Oxo-2,3-Dihydro-1,3-Benzoxazole-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.