Description

5-Benzoxazolesulfonylchloride,2,3-Dihydro-2-Oxo-(9Ci) is a specialized heterocyclic sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, acting as a reactive electrophile for sulfonamide formation and providing a benzoxazolone scaffold for medicinal chemistry. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who are developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes where the benzoxazolone moiety is a privileged scaffold.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by introducing the sulfonyl group into target molecules.
• Material Science: Building block for designing specialty polymers and functional materials with specific sulfonamide linkages.
• Chemical Biology: Useful as a probe or labeling reagent due to its reactive sulfonyl chloride group, which can modify proteins or other biomolecules.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	5-Benzoxazolesulfonylchloride,2,3-Dihydro-2-Oxo-(9Ci)
CAS No.	78633-41-7
Molecular Formula	C7H4ClNO4S
Molecular Weight	233.63 g/mol
Synonyms	2-Oxo-2,3-dihydro-1,3-benzoxazole-5-sulfonyl chloride; 5-Chlorosulfonyl-2-benzoxazolinone; 2-Benzoxazolinone-5-sulfonyl chloride; 2-Hydroxybenzoxazole-5-sulfonyl chloride; 2,3-Dihydro-2-oxobenzoxazole-5-sulfonyl chloride; 1,3-Benzoxazol-2(3H)-one, 5-(chlorosulfonyl)-; 5-(Chlorosulfonyl)-2(3H)-benzoxazolone
EINECS	Contact for details

Quality Control

Every batch of 5-Benzoxazolesulfonylchloride,2,3-Dihydro-2-Oxo-(9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.