Description

Quinine-10,11-Epoxide is a key epoxide derivative of the natural alkaloid quinine. This compound serves as a critical synthetic intermediate and reference standard in pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies involved in the synthesis of antimalarial agents, chiral catalysts, and for analytical method development. The product is supplied under stringent quality control to ensure consistency for sensitive applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel antimalarial compounds and other quinine-derived pharmaceuticals.
• Chiral Synthesis: Used as a precursor or reagent in asymmetric synthesis for creating enantiomerically pure molecules.
• Analytical Reference Standard: Serves as a high-purity standard for quality control (QC) and research & development (R&D) in analytical laboratories, particularly for HPLC and LC-MS methods.
• Metabolite Studies: Employed in pharmacological and metabolic research to study the biotransformation pathways of quinine and related alkaloids.
• Organic Chemistry Research: Utilized in academic and industrial research exploring epoxide chemistry, ring-opening reactions, and alkaloid modifications.

Basic Information

Product Name	Quinine-10,11-Epoxide
CAS No.	78523-31-6
Molecular Formula	C20H24N2O3
Molecular Weight	340.42 g/mol
Synonyms	10,11-Epoxyquinine; 10,11-α-Epoxyquinine; Quinine 10,11-epoxide; (8S,9R)-10,11-Epoxy-6'-methoxycinchonan-9-ol; Cinchonan-9-ol, 10,11-epoxy-6'-methoxy-, (8S,9R)-
EINECS	Contact for details

Quality Control

Our Quinine-10,11-Epoxide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity assessment by HPLC. A Certificate of Analysis (COA) detailing batch-specific results is provided to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.