Description

Methylmercury Glutathione is a well-defined organomercury conjugate, specifically the adduct formed between methylmercury and the tripeptide glutathione. This compound is of significant interest in toxicological and environmental research as a model for understanding the biochemical interactions and metabolic pathways of methylmercury, a potent neurotoxin. It serves as a critical reference standard and research reagent for scientists and laboratories investigating heavy metal toxicity, detoxification mechanisms, and biomarker development.

Application

• Toxicological Research: Used as a precise reference material in studies examining the metabolism, distribution, and excretion of methylmercury in biological systems.
• Environmental Analysis: Serves as a calibration standard for advanced analytical techniques (e.g., LC-MS, HPLC) to detect and quantify mercury species in environmental and biological samples.
• Biomarker Development: Employed in the development and validation of assays to measure specific mercury-glutathione conjugates as potential biomarkers of exposure.
• Biochemical Studies: Facilitates research into the role of glutathione in the cellular detoxification and transport mechanisms of heavy metals.
• Reference Standard Production: Acts as a high-purity starting material or comparator for certified reference material (CRM) manufacturers and analytical service providers.

Basic Information

Product Name	Methylmercury Glutathione
CAS No.	78505-11-0
Molecular Formula	C13H23HgN3O6S
Molecular Weight	542.00 g/mol
Synonyms	Methylmercury Glutathione Adduct; Glutathione Methylmercury Complex; L-γ-Glutamyl-L-cysteinylglycine Methylmercury; (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(methylmercurio)ethyl]carbamoyl}butanoic Acid; MeHg-GSH; Methylmercury(II) Glutathione; NSC 339041
EINECS	Contact for details

Quality Control

Every batch of our Methylmercury Glutathione is manufactured and analyzed under strict quality protocols to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay (by HPLC), heavy metal impurities, and residual solvents. Our quality system is designed to meet the exacting requirements of research and analytical standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.