Description

Lhrh, n-Ac-(4-F-Phe)(1)-(4-Cl-Phe)(2)-Trp(3,6)-Alanh2(10)- CAS NO 78493-49-9 is a synthetic, modified decapeptide analog of luteinizing hormone-releasing hormone (LHRH). This compound is engineered for enhanced stability and specific receptor binding affinity, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel therapeutic agents in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel LHRH antagonist or agonist drug candidates.
• Endocrinology Research: Used in biochemical and pharmacological studies to investigate the hypothalamic-pituitary-gonadal axis and hormone regulation.
• Oncology Research: Applied in the development of targeted therapies for hormone-dependent cancers, such as prostate and breast cancer.
• Peptide Chemistry R&D: Acts as a reference standard or substrate in method development for peptide synthesis, purification, and analysis.
• Bioconjugation Studies: Utilized in the creation of peptide-drug conjugates or diagnostic probes due to its modifiable structure.

Basic Information

Item	Details
Product Name	Lhrh, n-Ac-(4-F-Phe)(1)-(4-Cl-Phe)(2)-Trp(3,6)-Alanh2(10)- CAS NO 78493-49-9
CAS No.	78493-49-9
Molecular Formula	C64H78ClFN14O12
Molecular Weight	1241.82 g/mol
Synonyms	Ac-D-4-F-Phe-D-4-Cl-Phe-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Ala-NH2; Modified LHRH Decapeptide; LHRH Analog (4-F,4-Cl, D-Trp(3,6)); Gonadorelin Analog; Luteinizing Hormone-Releasing Hormone Derivative; [Ac-D-4-F-Phe1, D-4-Cl-Phe2, D-Trp3,6]-LHRH; 78493-49-9
EINECS	Contact for details

Quality Control

Our Lhrh analog is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the stringent requirements for research-grade peptides. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetic Acid Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.