Description

Urea-13C,15N2 is a stable isotope-labeled analog of urea, where all carbon atoms are the 13C isotope and both nitrogen atoms are the 15N isotope. This compound is an essential internal standard and tracer for advanced analytical research, enabling precise quantification and metabolic pathway analysis. It is primarily used by researchers and quality control laboratories in the pharmaceutical, environmental science, and clinical diagnostics industries.

Application

• Mass Spectrometry Internal Standard: Used as a quantitative reference standard in LC-MS and GC-MS analysis of urea in biological fluids (e.g., blood, urine) for clinical diagnostics and metabolomics studies.
• Metabolic Pathway Tracing: Serves as a crucial tracer in isotope dilution studies to investigate nitrogen and carbon metabolism in plants, animals, and microorganisms.
• Pharmaceutical Research: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of urea-containing compounds or related metabolic processes.
• Environmental Science: Applied in studies of the nitrogen cycle, including soil nitrification/denitrification processes and wastewater treatment analysis.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Acts as a labeled substrate for 13C and 15N NMR spectroscopy to elucidate molecular structures and dynamics.
• Certified Reference Material (CRM): Used in the preparation of high-precision calibration standards for analytical laboratories to ensure measurement accuracy and traceability.

Basic Information

Product Name	Urea-13C,15N2
CAS No.	78405-35-3
Molecular Formula	13C15N2H4O
Molecular Weight	62.03 g/mol
Synonyms	Urea-13C,15N2; [13C,15N2]-Urea; Carbonic-13C diamide-15N2; Urea (13C, 99%; 15N2, 99%); Isotopic Urea; Doubly Labeled Urea; 13C,15N2-Urea; Urea-13C,15N2 (Isotope Labeled)
EINECS	Contact for details

Quality Control

Our Urea-13C,15N2 is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 13C and 15N), chemical purity, and specific analytical results. We support compliance with cGMP and ISO 17034 (Reference Material Producer) standards for traceable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or storage under an inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99%
Isotopic Enrichment (Atom % 15N)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.