Description

One CAS NO 78394-25-9 is a high-purity chemical compound, also known as 2,4-Dichloro-5-fluoropyrimidine, valued for its role as a versatile building block in advanced organic synthesis. Its significance lies in its ability to introduce key halogenated pyrimidine scaffolds, which are critical for developing active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drugs.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides that require fluorinated pyrimidine structures.
• Chemical Research & Development: Serves as a crucial building block for creating novel heterocyclic compounds in academic and industrial R&D laboratories.
• Material Science: Employed in the synthesis of specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Custom Synthesis: Provides a foundational structure for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke molecules for clients.

Basic Information

Product Name	One CAS NO 78394-25-9
CAS No.	78394-25-9
Molecular Formula	C4HCl2FN2
Molecular Weight	166.96 g/mol
Synonyms	2,4-Dichloro-5-fluoropyrimidine; 5-Fluoro-2,4-dichloropyrimidine; 2,4-Dichloro-5-fluoro-1,3-diazine; Fluoropyrimidine derivative; Pyrimidine, 2,4-dichloro-5-fluoro-; FC Pyrimidine intermediate
EINECS	Contact for details

Quality Control

Our production of One CAS NO 78394-25-9 adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous standards demanded by pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.