Description

(5S)-5,6-Dihydrobenzo[A]Anthracene-5α,6α-Diol is a high-purity, stereochemically defined dihydrodiol derivative of benzo[a]anthracene. This compound is a critical intermediate in advanced organic synthesis and biochemical research, particularly in the study of polycyclic aromatic hydrocarbon (PAH) metabolism and DNA adduct formation. It is essential for researchers and manufacturers in the fields of analytical chemistry, toxicology, and pharmaceutical development who require precise and reliable reference standards for their work.

Application

• Biochemical Research Standard: Serves as a key reference material and metabolic intermediate in studies investigating the metabolic activation pathways of polycyclic aromatic hydrocarbons (PAHs).
• Toxicology and Carcinogenesis Studies: Used as a precise analytical standard to calibrate equipment and validate methods for detecting and quantifying PAH-DNA adducts, crucial for understanding mechanisms of chemical carcinogenesis.
• Pharmaceutical Intermediate: Acts as a sophisticated building block in the synthesis of complex molecules for drug discovery programs targeting specific enzymatic pathways.
• Analytical Chemistry: Employed as a high-purity calibration standard in HPLC, GC-MS, and other chromatographic techniques to ensure accurate quantification of PAH metabolites in environmental and biological samples.
• Environmental Monitoring: Supports method development for the sensitive detection of PAH derivatives and their biological impact markers in environmental health studies.

Basic Information

Product Name	(5S)-5,6-Dihydrobenzo[A]Anthracene-5α,6α-Diol
CAS No.	78306-74-8
Molecular Formula	C22H16O2
Molecular Weight	312.36 g/mol
Synonyms	(5S)-5,6-Dihydrobenzo[a]anthracene-5,6-diol; (5S)-Benzo[a]anthracene-5,6-dihydrodiol; (5S)-BA-5,6-diol; (5S)-Dihydrodiol Benzo[a]anthracene; (5S)-5,6-Dihydroxy-5,6-dihydrobenzo[a]anthracene; (5S)-BA 5,6-DHD; (+)-(5S,6S)-Dihydroxy-5,6-dihydrobenzo[a]anthracene
EINECS	Contact for details

Quality Control

Every batch of (5S)-5,6-Dihydrobenzo[A]Anthracene-5α,6α-Diol is manufactured under strict quality control protocols. Our products undergo rigorous analytical testing, including chiral HPLC and spectroscopic methods, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, chiral excess, and analytical results are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.